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  2. New blood test enables brain injury monitoring after stroke
News | 16/01/2026 | Research News

New blood test enables brain injury monitoring after stroke

Stroke is a medical emergency with rapidly evolving brain injury. But unlike other organs, the brain lacks a blood test to monitor acute injury. ISD researchers and international partners report that a new blood biomarker, brain-derived tau (BD-tau), can track brain injury after ischemic stroke, predict outcomes years later and reflect treatment effects. Now published in Science Translational Medicine!
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Vlegels N, Knuth NL, Steiner KA, Zhang L, Vix AL, Moumin D, Mirzen I, Khalifeh N, Forster C, Gesierich B, Müller F, Lohse P, Filler J, Fang R, Klein M, Dimitriadis K, Franzmeier N, Liebig T, Endres M, Goertler M, Petzold GC, Wunderlich S, Zerr I, Field TS, Pham M, Swartz RH, Poli S, Berrouschot J, Zafar A, Schneider H, Shankar JJ, Aamodt AH, Minnerup J, Mandzia JL, Reimann G, Psychogios MN, Mundiyanapurath S, Reich A, Yeo LLL, Duering M, Reidler P; DEMDAS study group; ESCAPE-NEXT biomarker substudy investigators‡; Goyal M, Tymianski M, Hill MD, Dichgans M, Tiedt S; DEMDAS study group collaborators; ESCAPE-NEXT biomarker substudy investigators. Brain-derived tau for monitoring brain injury in acute ischemic stroke. Sci Transl Med. 2026 Jan 14;18(832):eadz1280. doi: 10.1126/scitranslmed.adz1280. Epub 2026 Jan 14. 

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