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LMU Munich University Hospital

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ISD

Welcome to the Institute for Stroke and Dementia Research (ISD)

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News

An AIM2-inflammasome signaling cascade causes post-stroke immunosuppression and secondary infections.

March 2021 – Stroke patients are predisposed to life-threatening infections after the initial ischemic event. This phenomenon is caused by a severe state of post-injury immunosuppression, which is characterized by a loss of T cells. In a collaboration with investigators from Germany and China, Stefan Roth (Liesz Lab) demonstrates that monocytes sense injury-released cell-free DNA via the AIM2 inflammasome inducing extrinsic T cell death. Uncovering this mechanism could open up new therapeutical approaches...

Events

March 9th 2021, 5pm via Zoom

Dr. rer. nat. Jörg Klug

ISD Virtual Seminar Series

“Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44”

Events Overview

ISD Scientific Talk

Research Groups

Translational Research – Martin Dichgans

Vascular Biology – Jürgen Bernhagen

Vascular Cognitive Impairment – Marco Düring

Brain Imaging and Biomarker – Michael Ewers

Stroke-Immunology – Arthur Liesz

Neurobiology – Dominik Paquet

Experimental Stroke Research – Nikolaus Plesnila

Acute Brain Injury – Ali Ertürk

Microbiome-Gut-Brain Interactions – Corinne Benakis

Alzheimer’s Disease Neuroimaging – Nicolai Franzmeier

Systems Neuroscience – Ozgun Gokce

Oligodendrocyte Pathology – Sarah Jäkel

Molecular Biomarkers – Steffen Tiedt

Events overview

Research Groups Overview

Remote Events

March 9th 2021, 5pm:
ISD Virtual Seminar Series: Jörg Klug, Dr. rer. nat. “Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independent of its receptor CD74/CD44”

March 23d 2021, 4pm:

ISD Virtual Seminar Series: Savas Tay, PhD “Understanding signaling networks with single cell analysis and modeling”

Events Overview

People in front of ISD Building © Stefan-Müller-Naumann

Annual Report 2019/2020 PDF

Publications by the ISD

Research Support

Contact

Institute for Stroke and Dementia Research (ISD)
University Hospital, LMU Munich

Director: Prof. Dr. med. Martin Dichgans

Feodor-Lynen-Straße 17

81377 Munich, Germany

Phone: +49 (0)89 4400 46019
www.isd-research.de
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Partners

Neurologische Klinik und Poliklinik der Universität München

DZNE – Deutsches Zentrum für Neurodegenerative Erkrankungen

SyNergy – Munich Cluster for Systems Neurology

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© Institute for Stroke and Dementia Research (ISD)

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ISD Research

Research Groups
- DichgansLab
- BernhagenLab
- DueringLab
- LieszLab
- EwersLab
- PaquetLab
- PlesnilaLab
- ErturkLab
- BenakisLab
- Franzmeier Lab
- GokceLab
- JäkelLab
- TiedtLab
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