Welcome to the Institute for Stroke and Dementia Research (ISD) – Director: Prof. Martin Dichgans
Life’s simple 7 and incident dementia risk
March 2021 – Leveraging data from the UK Biobank (N=229,976 participants) ISD investigators examined whether cardiovascular health measured by the ‘Life’s simple 7’ score is associated with incident all-cause dementia. They found that higher blood pressure was associated with higher risk of dementia both in longitudinal and Mendelian Randomization analyses. These findings underscore the importance of blood pressure control in midlife to mitigate dementia risk...