News

June 2020

HDAC9 – from GWAS discovery to mechanisms and therapeutic targeting

Drug targets with support from human genetics have a higher probability of reaching phase III clinical trials and regulatory approval. Following their GWAS-based discovery of HDAC9 as a major risk locus for human atherosclerosis, ISD investigators identified a detailed mechanism linking HDAC9 to vascular inflammation. They further demonstrate that therapeutic inhibition of this HDAC9-dependent pathway confers plaque stability on top of atheroprotection …  

Events

July 7th 2020 4pm on Zoom:

“Pathophysiology of microvascular lesions in cerebral amyloid angiopathy”

Susanne van Veluw, PhD, Assistant Professor,
Harvard Medical School and Massachusetts General Hospital

STROKE & DEMENTIA RESEARCH: VIRTUAL SEMINAR SERIES
Brain imaging, vascular and neuronal systems, neuroimmunology and gut-brain axis...

Research Groups

DichgansLab – Translational Research

BernhagenLab – Vascular Biology

DueringLab – Vascular Cognitive Impairment

EwersLab – Brain Imaging and Biomarker

PlesnilaLab – Experimental Stroke Research

LieszLab – Stroke-Immunology

ErturkLab – Acute Brain Injury

PaquetLab – Neurobiology

BenakisLab – Microbiome-Gut-Brain Interactions