August 2020 | Alterations in the brain’s immune response are associated with higher risk of Alzheimer’s dementia, but the effect of microglia activation on amyloid-plaque deposition is elusive. ISD and DZNE investigators found higher CSF sTREM2 and TSPO PET, i.e. biomarkers of microglia activation, to be associated with lower amyloid accumulation in both mouse models of amyloid deposition and elderly individuals, suggesting a protective effect of TREM2-related microglia activity against a key Alzheimer’s pathology...
September 3rd 2020 5pm on Zoom:
B.R.A.I.N. lecture (Zoom):
Perminder Sachdev AM, MBBS, MD, PhD,Scientia Professor of Neuropsychiatry at UNSW Sydney (UNSW):