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                                                    News

                                                    Skull: A key new player in the neuro-immune axis

                                                    August 2023 – Neuroimmune interactions exhibit remarkable complexity, and exploring brain borders has gained significant attention in the quest for innovative approaches to diagnose, monitor, and treat brain pathologies. The recent discovery of connections between the skull and meninges has brought the skull into focus. A large collaborative research team led by the Erturk lab extensively examined the molecular and structural aspects of the skull in both mice and humans. Their findings demonstrated that skull inflammation can serve as an indicator of brain inflammation in patients suffering from diverse neurological disorders. >>

                                                    wildDISCO: A Revolutionary Whole Mouse Body Mapping Technique

                                                    July 2023 – Researchers at the Erturk lab have introduced wildDISCO, a groundbreaking method that utilizes standard antibodies to achieve deep penetration into the whole mouse body, generating high-resolution 3D atlases of neurons, immune cells, the vasculature, and lymphatic vessels. With unprecedented insights into anatomical and functional connections among multiple organs and systems, wildDISCO promises to revolutionize disease understanding, drug development, and medical education. >>

                                                    ISD Research Retreat

                                                    July 2023 – ISD research teams gathered for the annual scientific retreat to present their projects and discuss science. The meeting included presentations from Ph.D. students, an evening poster session, invited speaker talks, and focused workshops such as the one on AI by Hannah Spitzer. The meeting further served as an opportunity to familiarize people with the medium- and long-term strategy of ISD.

                                                    ESO Conference in Munich

                                                    May 2023 – The European Stroke Organisation Conference ESOC 2023 opened with a public awareness campaign and proceeded with an extensive scientific programme including the presentation of large international trials in plenaries, workshops, teaching courses and other formats. ISD researchers served as the local hosts and also presented results >>

                                                    STRIVE-2 Standards released

                                                    May 2023 – Small vessel disease (SVD) accounts for ~25% of strokes, more than doubles the risk of future stroke, and contributes to up to 45% of dementia cases. In 2013, STandards for ReportIng Vascular Changes on nEuroimaging 1 (STRIVE-1) categorised features of SVD that are visible on structural MRI and defined standards on multiple levels up to reporting. In an international effort with other experts ISD investigators now updated guidance on imaging of vascular changes in studies of ageing and neurodegeneration to create STRIVE-2 >>

                                                    EMBO Workshop

                                                    3rd EMBO Workshop on Stroke-Immunology

                                                    May 2023 – The 3rd edition of "The EMBO Workshop on Stroke-Immunology" will take place from September 18 to 21, 2023 at Schloss Hohenkammer in the iconic country side of Munich. The meeting provides a unique environment for scientists at all career levels to access recent advances in the rapidly evolving field of stroke and neuroimmunology research and to expand on collaborations. >>

                                                    Emmy Noether Award to Marios Georgakis

                                                    March 2023 – The DFG awarded an Emmy Noether Award to Marios Georgakis for establishing an independent junior research group focusing on the inflammatory mechanisms driving atheroprogression. His team will analyze high-dimensional data aiming to discover novel anti-inflammatory drug targets for cardiovascular disease, map molecular and histological immunophenotypes associated with atheroprogression, and uncover imaging and circulating biomarkers of human atheroinflammation >>

                                                    First LEDUCQ Network Meeting in NY City

                                                    March 2023 – The first biannual network meeting will be held on March 26-28, 2023 in New York City. Principal Investigators will present their research programs while also giving Early Career Investigators an opportunity to introduce their work. The International Network of Excellence on Brain Endothelium: A Nexus for Cerebral Small Vessel Disease (BRENDA) is coordinated by Martin Dichgans and Frank Faraci (Iowa) and funded by the Leducq Foundation >>

                                                    Hertie Network of Excellence in Clinical Neuroscience

                                                    Hertie Network of Excellence in Clinical Neuroscience approved for prolongation

                                                    January 2023 – The Hertie Foundation will continue funding for its Network of Excellence in Clinical Neuroscience. The program provides support to junior scientists (four from LMU and TUM) and facilitates collaborations across participating sites. The scientific focus of the Munich site (Speakers: M. Dichgans and Thomas Korn) is on neurovascular, neurodegenerative, and neuroinflammatory diseases and their underlying mechanisms. >>

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                                                    Institute for Stroke and Dementia Research (ISD)
                                                    University Hospital, LMU Munich

                                                    Director: Prof. Dr. med. Martin Dichgans

                                                    Feodor-Lynen-Straße 17
                                                    81377 Munich, Germany

                                                    Phone: +49 (0)89 4400 46019
                                                    www.isd-research.de
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                                                    Partners

                                                    Neurologische Klinik und Poliklinik der Universität München

                                                    DZNE – Deutsches Zentrum für Neurodegenerative Erkrankungen

                                                    SyNergy – Munich Cluster for Systems Neurology

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                                                    • Our Labs
                                                      • Dichgans Lab
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                                                      • Simons Lab
                                                      • Liesz Lab
                                                      • Ewers Lab
                                                      • Paquet Lab
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